Regulation of the Shareholders’ Meeting of Pharma Mar, S.A.

The Regulation of the Shareholders’ Meeting were approved by the General Meeting held on June 30, 2015, and registered in the Madrid’s Mercantile Register on October 30, 2015.

In view of the experience acquired with the application of the Regulation and of possible regulatory changes affecting its content, the Board of Directors will submit to the Shareholders’ Meeting any amendments that may be necessary in order to enhance the workings and efficiency of the Shareholders’ Meeting and facilitate the exercise of the shareholders’ rights.

General Shareholders’ Meeting Regulations